Table 5 Diagnostic accuracy of TRPS1, GATA3 and SOX10 for the diagnosis of breast carcinoma
From: Trichorhinophalangeal syndrome type 1 (TRPS1) in breast pathology: diagnostic utility and pitfalls
Immunomarker | Expression | Primary origin of cancer | Sensitivity | Specificity | PPV | NPV | Diagnostic accuracy | |
|---|---|---|---|---|---|---|---|---|
Breast | Others | |||||||
TRPS1 | Positive | 88 | 5 | 93.6% | 58.3% | 94.6% | 53.8% | 89.62% |
Negative | 6 | 7 | ||||||
GATA3 | Positive | 60 | 3 | 76.9% | 66.7% | 95.2% | 25% | 75.86% |
Negative | 18 | 6 | ||||||
SOX10 | Positive | 23 | 0 | 47.9% | 100% | 100% | 24.2% | 55.35% |
Negative | 25 | 8 | ||||||