Fig. 1

Poorly differentiated primary triple-negative breast carcinoma with TRPS1 expression. 1A: Low power hematoxylin and eosin (H & E)-stained section showing poorly differentiated carcinoma with dense background inflammatory infiltrate and a relatively circumscribed border. 1B: Higher power view (H & E)-section showing high grade solid pattern tumor growth. 1C: TRPS1 (low power) showing diffuse strong positive staining in both tumor cells and background benign normal breast ducts and lobules. 1D: TRPS1 (high power) showing nuclear positivity in both tumor (right) and normal breast parenchyma (left), serving as positive internal control